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Thrombospondin-1 Is Necessary for the Development and Repair of Corneal Nerves

Thrombospondin-1-deficient (TSP-1(−/−)) mice are used as an animal model of Sjögren’s Syndrome because they exhibit many of the symptoms associated with the autoimmune type of dry eye found in primary Sjögren’s Syndrome. This type of dry eye is linked to the inflammation of the lacrimal gland, conju...

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Detalles Bibliográficos
Autores principales: Tatematsu, Yukako, Khan, Qalbi, Blanco, Tomas, Bair, Jeffrey A., Hodges, Robin R., Masli, Sharmila, Dartt, Darlene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214039/
https://www.ncbi.nlm.nih.gov/pubmed/30332778
http://dx.doi.org/10.3390/ijms19103191