Fullerene Derivatives of Nucleoside HIV Reverse Transcriptase Inhibitors—In Silico Activity Prediction

Here we present new derivatives of nucleoside reverse transcriptase inhibitors with a C(20) fullerene. The computational chemistry methods used in this study evaluate affinity of designed compounds towards the HIV-1 reverse transcriptase (RT) binding site and select the most active ones. The best of...

Descripción completa

Detalles Bibliográficos
Autores principales: Dąbrowska, Aleksandra, Pieńko, Tomasz, Taciak, Przemysław, Wiktorska, Katarzyna, Chilmonczyk, Zdzisław, Mazurek, Aleksander P., Stasiulewicz, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214040/
https://www.ncbi.nlm.nih.gov/pubmed/30347655
http://dx.doi.org/10.3390/ijms19103231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214040/
https://www.ncbi.nlm.nih.gov/pubmed/30347655
http://dx.doi.org/10.3390/ijms19103231

Ejemplares similares