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The Emerging Role of Cyclin-Dependent Kinases (CDKs) in Pancreatic Ductal Adenocarcinoma

The family of cyclin-dependent kinases (CDKs) has critical functions in cell cycle regulation and controlling of transcriptional elongation. Moreover, dysregulated CDKs have been linked to cancer initiation and progression. Pharmacological CDK inhibition has recently emerged as a novel and promising...

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Detalles Bibliográficos
Autores principales: García-Reyes, Balbina, Kretz, Anna-Laura, Ruff, Jan-Philipp, von Karstedt, Silvia, Hillenbrand, Andreas, Knippschild, Uwe, Henne-Bruns, Doris, Lemke, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214075/
https://www.ncbi.nlm.nih.gov/pubmed/30340359
http://dx.doi.org/10.3390/ijms19103219