Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress

Incomplete and low-fidelity genome duplication contribute to genomic instability and cancer development. Difficult-to-Replicate Sequences, or DiToRS, are natural impediments in the genome that require specialized DNA polymerases and repair pathways to complete and maintain faithful DNA synthesis. Di...

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Detalles Bibliográficos
Autores principales: Tsao, Wei-Chung, Eckert, Kristin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214091/
https://www.ncbi.nlm.nih.gov/pubmed/30347795
http://dx.doi.org/10.3390/ijms19103255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214091/
https://www.ncbi.nlm.nih.gov/pubmed/30347795
http://dx.doi.org/10.3390/ijms19103255

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