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Relationship between the Regulation of Caspase-8-Mediated Apoptosis and Radioresistance in Human THP-1-Derived Macrophages

Radiosensitivity varies depending on the cell type; highly differentiated cells typically exhibit greater radioresistance. We recently demonstrated that human macrophages derived from THP-1 monocytic cells, which lack TP53, are highly resistant to radiation-induced apoptosis compared with undifferen...

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Detalles Bibliográficos
Autores principales: Yoshino, Hironori, Konno, Haruka, Ogura, Koya, Sato, Yoshiaki, Kashiwakura, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214119/
https://www.ncbi.nlm.nih.gov/pubmed/30322167
http://dx.doi.org/10.3390/ijms19103154