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Relevance of Breast Cancer Resistance Protein to Pharmacokinetics of Florfenicol in Chickens: A Perspective from In Vivo and In Vitro Studies

Florfenicol (FFC) is a valuable synthetic fluorinated derivative of thiamphenicol widely used to treat infectious diseases in food animals. The aims of the study were to investigate whether FFC is a substrate for the breast cancer resistance protein (BCRP) and whether the transporter influences oral...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Guo, Li, Zloh, Mire, Zhang, Yujuan, Huang, Jinhu, Wang, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214120/
https://www.ncbi.nlm.nih.gov/pubmed/30326566
http://dx.doi.org/10.3390/ijms19103165