Bivalent Ligand UDCA-LPE Inhibits Pro-Fibrogenic Integrin Signalling by Inducing Lipid Raft-Mediated Internalization

Ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE) is a synthetic bile acid-phospholipid conjugate with profound hepatoprotective and anti-fibrogenic functions in vitro and in vivo. Herein, we aimed to demonstrate the inhibitory effects of UDCA-LPE on pro-fibrogenic integrin signalling. UDCA-LP...

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Detalles Bibliográficos
Autores principales: Su, Jie, Gan-Schreier, Hongying, Goeppert, Benjamin, Chamulitrat, Walee, Stremmel, Wolfgang, Pathil, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214129/
https://www.ncbi.nlm.nih.gov/pubmed/30347788
http://dx.doi.org/10.3390/ijms19103254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214129/
https://www.ncbi.nlm.nih.gov/pubmed/30347788
http://dx.doi.org/10.3390/ijms19103254

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