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Bivalent Ligand UDCA-LPE Inhibits Pro-Fibrogenic Integrin Signalling by Inducing Lipid Raft-Mediated Internalization

Ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE) is a synthetic bile acid-phospholipid conjugate with profound hepatoprotective and anti-fibrogenic functions in vitro and in vivo. Herein, we aimed to demonstrate the inhibitory effects of UDCA-LPE on pro-fibrogenic integrin signalling. UDCA-LP...

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Detalles Bibliográficos
Autores principales:	Su, Jie, Gan-Schreier, Hongying, Goeppert, Benjamin, Chamulitrat, Walee, Stremmel, Wolfgang, Pathil, Anita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214129/ https://www.ncbi.nlm.nih.gov/pubmed/30347788 http://dx.doi.org/10.3390/ijms19103254

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