Targeting Oncogenic Signaling in Mutant FLT3 Acute Myeloid Leukemia: The Path to Least Resistance

The identification of recurrent driver mutations in genes encoding tyrosine kinases has resulted in the development of molecularly-targeted treatment strategies designed to improve outcomes for patients diagnosed with acute myeloid leukemia (AML). The receptor tyrosine kinase FLT3 is the most common...

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Detalles Bibliográficos
Autores principales: Staudt, Dilana, Murray, Heather C., McLachlan, Tabitha, Alvaro, Frank, Enjeti, Anoop K., Verrills, Nicole M., Dun, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214138/
https://www.ncbi.nlm.nih.gov/pubmed/30332834
http://dx.doi.org/10.3390/ijms19103198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214138/
https://www.ncbi.nlm.nih.gov/pubmed/30332834
http://dx.doi.org/10.3390/ijms19103198

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