Proprotein convertase inhibition promotes ciliated cell differentiation – a potential mechanism for the inhibition of Notch1 signalling by decanoyl‐RVKR‐chloromethylketone

Chronic repetitive rounds of injury and repair in the airway lead to airway remodelling, including ciliated cell loss and mucous cell hyperplasia. Airway remodelling is mediated by many growth and differentiation factors including Notch1, which are proteolytically processed by proprotein convertases...

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Detalles Bibliográficos
Autores principales: Lee, Sang‐Nam, Choi, In‐Suk, Kim, Hyun Jun, Yang, Eun Jin, Min, Hyun Jin, Yoon, Joo‐Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214225/
https://www.ncbi.nlm.nih.gov/pubmed/27878968
http://dx.doi.org/10.1002/term.2240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214225/
https://www.ncbi.nlm.nih.gov/pubmed/27878968
http://dx.doi.org/10.1002/term.2240

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