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Statistical Binning for Barcoded Reads Improves Downstream Analyses

Sequencing technologies are capturing longer-range genomic information at lower error rates, enabling alignment to genomic regions that are inaccessible with short reads. However, many methods are unable to align reads to much of the genome, recognized as important in disease, and thus report errone...

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Detalles Bibliográficos
Autores principales: Shajii, Ariya, Numanagić, Ibrahim, Whelan, Christopher, Berger, Bonnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214366/
https://www.ncbi.nlm.nih.gov/pubmed/30138581
http://dx.doi.org/10.1016/j.cels.2018.07.005