Stem cell factor and NSC87877 combine to enhance c-Kit mediated proliferation of human megakaryoblastic cells

Enhancement of hematopoietic stem cells (HSCs) proliferation is a central aim in bone marrow transplantation (BMT). A stem cell factor (SCF) and c-Kit mediated extracellular signaling trigger proliferation of HSCs. This signaling is negatively regulated by protein tyrosine phosphatases (PTPs), SHP-1...

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Detalles Bibliográficos
Autores principales: Raghav, Pawan Kumar, Singh, Ajay Kumar, Gangenahalli, Gurudutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214509/
https://www.ncbi.nlm.nih.gov/pubmed/30388134
http://dx.doi.org/10.1371/journal.pone.0206364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214509/
https://www.ncbi.nlm.nih.gov/pubmed/30388134
http://dx.doi.org/10.1371/journal.pone.0206364

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