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Stem cell factor and NSC87877 combine to enhance c-Kit mediated proliferation of human megakaryoblastic cells
Enhancement of hematopoietic stem cells (HSCs) proliferation is a central aim in bone marrow transplantation (BMT). A stem cell factor (SCF) and c-Kit mediated extracellular signaling trigger proliferation of HSCs. This signaling is negatively regulated by protein tyrosine phosphatases (PTPs), SHP-1...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214509/ https://www.ncbi.nlm.nih.gov/pubmed/30388134 http://dx.doi.org/10.1371/journal.pone.0206364 |