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GATA3 is downregulated in osteosarcoma and facilitates EMT as well as migration through regulation of slug

BACKGROUND: GATA3 functions as a tumor suppressor and has been observed in multiple types of cancer, but the effects and mechanisms of GATA3 in osteosarcoma (OS) are not yet known. METHODS: The GATA3 expression in OS cells and tissues were detected using quantitative reverse-transcription PCR and We...

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Detalles Bibliográficos
Autores principales: Ma, Linjie, Xue, Wentao, Ma, Xianghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214586/
https://www.ncbi.nlm.nih.gov/pubmed/30464506
http://dx.doi.org/10.2147/OTT.S176534