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GATA3 is downregulated in osteosarcoma and facilitates EMT as well as migration through regulation of slug
BACKGROUND: GATA3 functions as a tumor suppressor and has been observed in multiple types of cancer, but the effects and mechanisms of GATA3 in osteosarcoma (OS) are not yet known. METHODS: The GATA3 expression in OS cells and tissues were detected using quantitative reverse-transcription PCR and We...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214586/ https://www.ncbi.nlm.nih.gov/pubmed/30464506 http://dx.doi.org/10.2147/OTT.S176534 |