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BMP-2 inhibits lung metastasis of osteosarcoma: an early investigation using an orthotopic model
BACKGROUND: Bone morphogenetic proteins (BMPs), members of the TGF-β superfamily, are known to regulate cell proliferation, differentiation, apoptosis, chemotaxis, and angiogenesis. BMPs also participate in the development of most tissues and organs in vertebrates. Recombinant human (rh) BMPs, such...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214601/ https://www.ncbi.nlm.nih.gov/pubmed/30464502 http://dx.doi.org/10.2147/OTT.S176724 |