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BMP-2 inhibits lung metastasis of osteosarcoma: an early investigation using an orthotopic model

BACKGROUND: Bone morphogenetic proteins (BMPs), members of the TGF-β superfamily, are known to regulate cell proliferation, differentiation, apoptosis, chemotaxis, and angiogenesis. BMPs also participate in the development of most tissues and organs in vertebrates. Recombinant human (rh) BMPs, such...

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Detalles Bibliográficos
Autores principales: Xiong, Qisheng, Wang, Xuesong, Wang, Lizhen, Huang, Yan, Tian, Xiaodong, Fan, Yubo, Lin, Chia-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214601/
https://www.ncbi.nlm.nih.gov/pubmed/30464502
http://dx.doi.org/10.2147/OTT.S176724