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Combined Skin and Muscle DNA Priming Provides Enhanced Humoral Responses to a Human Immunodeficency Virus Type 1 Clade C Envelope Vaccine

Intradermal (i.d.) and intramuscular (i.m.) injections when administered with or without electroporation (EP) have the potential to tailor the immune response to DNA vaccination. This Phase I randomized controlled clinical trial in human immunodeficiency virus type 1–negative volunteers investigated...

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Detalles Bibliográficos
Autores principales: Cheeseman, Hannah Mary, Day, Suzanne, McFarlane, Leon Robert, Fleck, Sue, Miller, Aleisha, Cole, Tom, Sousa-Santos, Nelson, Cope, Alethea, Cizmeci, Deniz, Tolazzi, Monica, Hwekwete, Edith, Hannaman, Drew, Kratochvil, Sven, McKay, Paul Francis, Chung, Amy W., Kent, Stephen J., Cook, Adrian, Scarlatti, Gabriella, Abraham, Sonya, Combadiere, Behazine, McCormack, Sheena, Lewis, David John, Shattock, Robin John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214652/
https://www.ncbi.nlm.nih.gov/pubmed/30027768
http://dx.doi.org/10.1089/hum.2018.075