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miR-137 is a tumor suppressor in endometrial cancer and is repressed by DNA hypermethylation

Endometrial cancer is the most common gynecological cancer in the U.S. We wanted to identify epigenetic aberrations involving microRNAs (miRNAs), whose genes become hypermethylated in endometrial primary tumors. By integrating known miRNA sequences from the miRNA database (miRBase) with DNA methylat...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Chen, Jo-Hsin, Shan, Tianjiao, Aguilera-Barrantes, Irene, Wang, Li-Shu, Huang, Tim Hui-Ming, Rader, Janet S., Sheng, Xiugui, Huang, Yi-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214735/
https://www.ncbi.nlm.nih.gov/pubmed/29955087
http://dx.doi.org/10.1038/s41374-018-0092-x