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miR-137 is a tumor suppressor in endometrial cancer and is repressed by DNA hypermethylation
Endometrial cancer is the most common gynecological cancer in the U.S. We wanted to identify epigenetic aberrations involving microRNAs (miRNAs), whose genes become hypermethylated in endometrial primary tumors. By integrating known miRNA sequences from the miRNA database (miRBase) with DNA methylat...
Autores principales: | Zhang, Wei, Chen, Jo-Hsin, Shan, Tianjiao, Aguilera-Barrantes, Irene, Wang, Li-Shu, Huang, Tim Hui-Ming, Rader, Janet S., Sheng, Xiugui, Huang, Yi-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214735/ https://www.ncbi.nlm.nih.gov/pubmed/29955087 http://dx.doi.org/10.1038/s41374-018-0092-x |
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