Histone Deacetylase Inhibitor Suberanilohydroxamic Acid Treatment Reverses Hyposensitivity to γ‐Aminobutyric Acid in the Ventral Tegmental Area During Ethanol Withdrawal

BACKGROUND: The ventral tegmental area (VTA) is important for alcohol‐related reward and reinforcement. Mouse VTA neurons are hyposensitive to γ‐aminobutyric acid (GABA) during ethanol (EtOH) withdrawal, and GABA responsiveness is normalized by in vitro treatment with histone deacetylase inhibitors...

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Detalles Bibliográficos
Autores principales: You, Chang, Vandegrift, Bertha J., Zhang, Huaibo, Lasek, Amy W., Pandey, Subhash C., Brodie, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214766/
https://www.ncbi.nlm.nih.gov/pubmed/30103280
http://dx.doi.org/10.1111/acer.13870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214766/
https://www.ncbi.nlm.nih.gov/pubmed/30103280
http://dx.doi.org/10.1111/acer.13870

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