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MicroRNA-96 Promotes Schistosomiasis Hepatic Fibrosis in Mice by Suppressing Smad7

Infection with Schistosoma causes aberrant expression of host microRNAs (miRNAs), and normalizing the levels of dysregulated miRNAs can attenuate pathology. Here, we show that the host miRNA, miR-96, is markedly upregulated during the progression of hepatic schistosomiasis. We demonstrate that eleva...

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Detalles Bibliográficos
Autores principales: Luo, Xufeng, Zhang, Dongmei, Xie, Jun, Su, Qin, He, Xing, Bai, Ruipu, Gao, Guangping, Pan, Weiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214875/
https://www.ncbi.nlm.nih.gov/pubmed/30406154
http://dx.doi.org/10.1016/j.omtm.2018.10.002