An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2

α-N-terminal methylation of proteins is an important post-translational modification that is catalyzed by two different N-terminal methyltransferases, namely NTMT1 and NTMT2. Previous studies have suggested that NTMT1 is a tri-methyltransferase, whereas NTMT2 is a mono-methyltransferase. Here, we re...

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Detalles Bibliográficos
Autores principales: Dong, Cheng, Dong, Guangping, Li, Li, Zhu, Licheng, Tempel, Wolfram, Liu, Yanli, Huang, Rong, Min, Jinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214909/
https://www.ncbi.nlm.nih.gov/pubmed/30417120
http://dx.doi.org/10.1038/s42003-018-0196-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214909/
https://www.ncbi.nlm.nih.gov/pubmed/30417120
http://dx.doi.org/10.1038/s42003-018-0196-2

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