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Loss of embryonic neural crest derived cardiomyocytes causes adult onset hypertrophic cardiomyopathy in zebrafish

Neural crest cells migrate to the embryonic heart and transform into a small number of cardiomyocytes, but their functions in the developing and adult heart are unknown. Here, we show that neural crest derived cardiomyocytes (NC-Cms) in the zebrafish ventricle express Notch ligand jag2b, are adjacen...

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Detalles Bibliográficos
Autores principales: Abdul-Wajid, Sarah, Demarest, Bradley L., Yost, H. Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214924/
https://www.ncbi.nlm.nih.gov/pubmed/30389937
http://dx.doi.org/10.1038/s41467-018-07054-8