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An information-theoretic framework for deciphering pleiotropic and noisy biochemical signaling
Many components of signaling pathways are functionally pleiotropic, and signaling responses are marked with substantial cell-to-cell heterogeneity. Therefore, biochemical descriptions of signaling require quantitative support to explain how complex stimuli (inputs) are encoded in distinct activities...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214929/ https://www.ncbi.nlm.nih.gov/pubmed/30389942 http://dx.doi.org/10.1038/s41467-018-07085-1 |