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An information-theoretic framework for deciphering pleiotropic and noisy biochemical signaling

Many components of signaling pathways are functionally pleiotropic, and signaling responses are marked with substantial cell-to-cell heterogeneity. Therefore, biochemical descriptions of signaling require quantitative support to explain how complex stimuli (inputs) are encoded in distinct activities...

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Detalles Bibliográficos
Autores principales:	Jetka, Tomasz, Nienałtowski, Karol, Filippi, Sarah, Stumpf, Michael P. H., Komorowski, Michał
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214929/ https://www.ncbi.nlm.nih.gov/pubmed/30389942 http://dx.doi.org/10.1038/s41467-018-07085-1

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