PMA inhibits endothelial cell migration through activating the PKC-δ/Syk/NF-κB-mediated up-regulation of Thy-1

We previously showed that overexpression of Thy-1 inhibited and knock-down of Thy-1 enhanced endothelial cell migration. Here, we used phorbol-12-myristate-13-acetate (PMA) as an inducer for Thy-1 expression to investigate molecular mechanisms underlying Thy-1 up-regulation. Our data showed that inc...

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Detalles Bibliográficos
Autores principales: Wen, Heng-Ching, Huo, Yen Nien, Chou, Chih-Ming, Lee, Wen-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214930/
https://www.ncbi.nlm.nih.gov/pubmed/30389973
http://dx.doi.org/10.1038/s41598-018-34548-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214930/
https://www.ncbi.nlm.nih.gov/pubmed/30389973
http://dx.doi.org/10.1038/s41598-018-34548-8

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