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Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon

A significant portion of genes in vertebrate genomes belongs to multigene families, with each family containing several gene copies whose presence/absence, as well as isoform structure, can be highly variable across individuals. Existing de novo techniques for assaying the sequences of such highly-s...

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Detalles Bibliográficos
Autores principales: Sahlin, Kristoffer, Tomaszkiewicz, Marta, Makova, Kateryna D., Medvedev, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214943/
https://www.ncbi.nlm.nih.gov/pubmed/30389934
http://dx.doi.org/10.1038/s41467-018-06910-x