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Crystal Structure of Human Nocturnin Catalytic Domain

Nocturnin (NOCT) helps the circadian clock to adjust metabolism according to day and night activity. NOCT is upregulated in early evening and it has been proposed that NOCT serves as a deadenylase for metabolic enzyme mRNAs. We present a 2.7-Å crystal structure of the catalytic domain of human NOCT....

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Detalles Bibliográficos
Autores principales: Estrella, Michael A., Du, Jin, Korennykh, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214945/
https://www.ncbi.nlm.nih.gov/pubmed/30389976
http://dx.doi.org/10.1038/s41598-018-34615-0