Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer

Usnic acid (UA), a lichen secondary substance, has considerable anticancer activity in vitro, whereas its effect in vivo is limited. Here, potassium usnate (KU) was prepared by the salinization of UA to enhance its water solubility. KU showed increased bioavailability compared with UA in the tumor,...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Bae, Woo Kyun, Lee, Ji-Yoon, Choi, Yong Jae, Lee, Kyung Hwa, Park, Myong-Suk, Yu, Young Hyun, Park, So-Yeon, Zhou, Rui, Taş, İsa, Gamage, Chathurika, Paik, Man-Jeong, Lee, Jae Hyuk, Chung, Ik Joo, Kim, Kyung Keun, Hur, Jae-Seoun, Kim, Sang Kyum, Ha, Hyung-Ho, Kim, Hangun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214985/
https://www.ncbi.nlm.nih.gov/pubmed/30390003
http://dx.doi.org/10.1038/s41598-018-34709-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214985/
https://www.ncbi.nlm.nih.gov/pubmed/30390003
http://dx.doi.org/10.1038/s41598-018-34709-9

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