Cargando…

Effects of metformin on congenital muscular dystrophy type 1A disease progression in mice: a gender impact study

Congenital muscular dystrophy with laminin α2 chain-deficiency (LAMA2-CMD) is a severe muscle disorder with complex underlying pathogenesis. We have previously employed profiling techniques to elucidate molecular patterns and demonstrated significant metabolic impairment in skeletal muscle from LAMA...

Descripción completa

Detalles Bibliográficos
Autores principales: Fontes-Oliveira, Cibely C., M. Soares Oliveira, Bernardo, Körner, Zandra, M. Harandi, Vahid, Durbeej, Madeleine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214987/
https://www.ncbi.nlm.nih.gov/pubmed/30389963
http://dx.doi.org/10.1038/s41598-018-34362-2