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Single molecule localisation microscopy reveals how HIV-1 Gag proteins sense membrane virus assembly sites in living host CD4 T cells

Monitoring virus assembly at the nanoscale in host cells remains a major challenge. Human immunodeficiency virus type 1 (HIV-1) components are addressed to the plasma membrane where they assemble to form spherical particles of 100 nm in diameter. Interestingly, HIV-1 Gag protein expression alone is...

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Detalles Bibliográficos
Autores principales: Floderer, Charlotte, Masson, Jean-Baptiste, Boilley, Elise, Georgeault, Sonia, Merida, Peggy, El Beheiry, Mohamed, Dahan, Maxime, Roingeard, Philippe, Sibarita, Jean-Baptiste, Favard, Cyril, Muriaux, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214999/
https://www.ncbi.nlm.nih.gov/pubmed/30389967
http://dx.doi.org/10.1038/s41598-018-34536-y