Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing

HIV-1 Tat protein is released from HIV-1-infected cells and can enter non-permissive cells including neurons. Tat disrupts neuronal homeostasis and may contribute to the neuropathogenesis in people living with HIV (PLWH). The use of cocaine by PLWH exacerbates neuronal dysfunction. Here, we examined...

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Detalles Bibliográficos
Autores principales: Mohseni Ahooyi, Taha, Shekarabi, Masoud, Torkzaban, Bahareh, Langford, T. Dianne, Burdo, Tricia H., Gordon, Jennifer, Datta, Prasun K., Amini, Shohreh, Khalili, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215004/
https://www.ncbi.nlm.nih.gov/pubmed/30390000
http://dx.doi.org/10.1038/s41598-018-34539-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215004/
https://www.ncbi.nlm.nih.gov/pubmed/30390000
http://dx.doi.org/10.1038/s41598-018-34539-9

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