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Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing
HIV-1 Tat protein is released from HIV-1-infected cells and can enter non-permissive cells including neurons. Tat disrupts neuronal homeostasis and may contribute to the neuropathogenesis in people living with HIV (PLWH). The use of cocaine by PLWH exacerbates neuronal dysfunction. Here, we examined...
Autores principales: | Mohseni Ahooyi, Taha, Shekarabi, Masoud, Torkzaban, Bahareh, Langford, T. Dianne, Burdo, Tricia H., Gordon, Jennifer, Datta, Prasun K., Amini, Shohreh, Khalili, Kamel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215004/ https://www.ncbi.nlm.nih.gov/pubmed/30390000 http://dx.doi.org/10.1038/s41598-018-34539-9 |
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