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Suppressive effect of syndecan ectodomains and N-desulfated heparins on osteoclastogenesis via direct binding to macrophage-colony stimulating factor

Syndecans, a family of cell surface heparan sulfate proteoglycans, regulate cell differentiation via binding of their heparan sulfate chains to growth factors and cytokines and play a role in tumor growth and progression, wound repair, and intestinal mucosal damage. However, the functional and mecha...

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Detalles Bibliográficos
Autores principales: Kim, Jin-Man, Lee, Kyunghee, Kim, Mi Yeong, Shin, Hong-In, Jeong, Daewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215006/
https://www.ncbi.nlm.nih.gov/pubmed/30389911
http://dx.doi.org/10.1038/s41419-018-1167-8