Purification and Characterization of JZTx-14, a Potent Antagonist of Mammalian and Prokaryotic Voltage-Gated Sodium Channels

Exploring the interaction of ligands with voltage-gated sodium channels (Na(V)s) has advanced our understanding of their pharmacology. Herein, we report the purification and characterization of a novel non-selective mammalian and bacterial Na(V)s toxin, JZTx-14, from the venom of the spider Chilobra...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Tang, Dongfang, Liu, Shuangyu, Hu, Haoliang, Liang, Songping, Tang, Cheng, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215091/
https://www.ncbi.nlm.nih.gov/pubmed/30308978
http://dx.doi.org/10.3390/toxins10100408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215091/
https://www.ncbi.nlm.nih.gov/pubmed/30308978
http://dx.doi.org/10.3390/toxins10100408

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