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The Effects of Autophagy and PI3K/AKT/m-TOR Signaling Pathway on the Cell-Cycle Arrest of Rats Primary Sertoli Cells Induced by Zearalenone

A high concentration of Zearalenone (ZEA) will perturb the differentiation of germ cells, and induce a death of germ cells, but the toxic mechanism and molecular mechanism remain unclear. The Sertoli cells (SCs) play an irreplaceable role in spermatogenesis. In order to explore the potential mechani...

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Detalles Bibliográficos
Autores principales: Wang, Bing-jie, Zheng, Wang-long, Feng, Nan-nan, Wang, Tao, Zou, Hui, Gu, Jian-hong, Yuan, Yan, Liu, Xue-zhong, Liu, Zong-ping, Bian, Jian-chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215106/
https://www.ncbi.nlm.nih.gov/pubmed/30274213
http://dx.doi.org/10.3390/toxins10100398