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Molecular Modeling Studies on the Interactions of Aflatoxin B1 and Its Metabolites with Human Acetylcholinesterase. Part II: Interactions with the Catalytic Anionic Site (CAS)

The most common type of aflatoxin (AFT) found in nature is aflatoxin B1 (AFB1). This micotoxin is extremely hepatotoxic and carcinogenic to mammals, with acute and chronic effects. It is believed that this could be related to the capacity of AFB1 and its metabolites in inhibiting the enzyme acetylch...

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Detalles Bibliográficos
Autores principales: de Almeida, Joyce S. F. D., Dolezal, Rafael, Krejcar, Ondrej, Kuca, Kamil, Musilek, Kamil, Jun, Daniel, França, Tanos C. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215247/
https://www.ncbi.nlm.nih.gov/pubmed/30257474
http://dx.doi.org/10.3390/toxins10100389