Variations in the Botulinum Neurotoxin Binding Domain and the Potential for Novel Therapeutics

Botulinum neurotoxins (BoNTs) are categorised into immunologically distinct serotypes BoNT/A to /G). Each serotype can also be further divided into subtypes based on differences in amino acid sequence. BoNTs are ~150 kDa proteins comprised of three major functional domains: an N-terminal zinc metall...

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Detalles Bibliográficos
Autores principales: Davies, Jonathan R., Liu, Sai Man, Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215321/
https://www.ncbi.nlm.nih.gov/pubmed/30347838
http://dx.doi.org/10.3390/toxins10100421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215321/
https://www.ncbi.nlm.nih.gov/pubmed/30347838
http://dx.doi.org/10.3390/toxins10100421

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