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Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer’s disease

BACKGROUND: Biomarkers that can track disease onset and progression in autosomal dominant Alzheimer’s disease (ADAD) are needed. We investigate whether serum neurofilament light (NfL) concentration is associated with clinical and cerebrospinal fluid (CSF) markers in ADAD. We also evaluate serum NfL...

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Detalles Bibliográficos
Autores principales: Sánchez-Valle, Raquel, Heslegrave, Amanda, Foiani, Martha S., Bosch, Beatriz, Antonell, Anna, Balasa, Mircea, Lladó, Albert, Zetterberg, Henrik, Fox, Nick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215337/
https://www.ncbi.nlm.nih.gov/pubmed/30390718
http://dx.doi.org/10.1186/s13195-018-0439-y