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Essential roles of mitochondrial and heme function in lung cancer bioenergetics and tumorigenesis

Contrary to Warburg’s hypothesis, mitochondrial oxidative phosphorylation (OXPHOS) contributes significantly to fueling cancer cells. Several recent studies have demonstrated that radiotherapy-resistant and chemotherapy-resistant cancer cells depend on OXPHOS for survival and progression. Several ca...

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Detalles Bibliográficos
Autores principales: Kalainayakan, Sarada Preeta, FitzGerald, Keely E., Konduri, Purna Chaitanya, Vidal, Chantal, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215344/
https://www.ncbi.nlm.nih.gov/pubmed/30410721
http://dx.doi.org/10.1186/s13578-018-0257-8