A model of mucopolysaccharidosis type IIIB in pigs

Mucopolysaccharidosis type IIIB (MPS IIIB) is a rare genetic disorder caused by loss-of-function mutations in the NAGLU gene. Pigs are an ideal large animal model for human diseases; however, a porcine model of MPS IIIB has not been reported. We have previously generated a heterozygous NAGLU-deficie...

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Detalles Bibliográficos
Autores principales: Yang, Qiang, Zhao, Xueyan, Xing, Yuyun, Jiang, Chao, Jiang, Kai, Xu, Pan, Liu, Weiwei, Ren, Jun, Huang, Lusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215415/
https://www.ncbi.nlm.nih.gov/pubmed/30257828
http://dx.doi.org/10.1242/bio.035386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215415/
https://www.ncbi.nlm.nih.gov/pubmed/30257828
http://dx.doi.org/10.1242/bio.035386

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