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A model of mucopolysaccharidosis type IIIB in pigs

Mucopolysaccharidosis type IIIB (MPS IIIB) is a rare genetic disorder caused by loss-of-function mutations in the NAGLU gene. Pigs are an ideal large animal model for human diseases; however, a porcine model of MPS IIIB has not been reported. We have previously generated a heterozygous NAGLU-deficie...

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Detalles Bibliográficos
Autores principales:	Yang, Qiang, Zhao, Xueyan, Xing, Yuyun, Jiang, Chao, Jiang, Kai, Xu, Pan, Liu, Weiwei, Ren, Jun, Huang, Lusheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215415/ https://www.ncbi.nlm.nih.gov/pubmed/30257828 http://dx.doi.org/10.1242/bio.035386

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