A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies

Huntington's disease (HD) is a monogenic, progressive, neurodegenerative disorder with currently no available treatment. The Libechov transgenic minipig model for HD (TgHD) displays neuroanatomical similarities to humans and exhibits slow disease progression, and is therefore more powerful than...

Descripción completa

Detalles Bibliográficos
Autores principales: Askeland, Georgina, Rodinova, Marie, Štufková, Hana, Dosoudilova, Zaneta, Baxa, Monika, Smatlikova, Petra, Bohuslavova, Bozena, Klempir, Jiri, Nguyen, The Duong, Kuśnierczyk, Anna, Bjørås, Magnar, Klungland, Arne, Hansikova, Hana, Ellederova, Zdenka, Eide, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215428/
https://www.ncbi.nlm.nih.gov/pubmed/30254085
http://dx.doi.org/10.1242/dmm.035949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215428/
https://www.ncbi.nlm.nih.gov/pubmed/30254085
http://dx.doi.org/10.1242/dmm.035949

Ejemplares similares