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Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs

Miniature pigs have advantages over rodents in modeling atherosclerosis because their cardiovascular system and physiology are similar to that of humans. Apolipoprotein E (ApoE) deficiency has long been implicated in cardiovascular disease in humans. To establish an improved large animal model of fa...

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Detalles Bibliográficos
Autores principales: Fang, Bin, Ren, Xueyang, Wang, Ying, Li, Ze, Zhao, Lihua, Zhang, Manling, Li, Chu, Zhang, Zhengwei, Chen, Lei, Li, Xiaoxue, Liu, Jiying, Xiong, Qiang, Zhang, Lining, Jin, Yong, Liu, Xiaorui, Li, Lin, Wei, Hong, Yang, Haiyuan, Li, Rongfeng, Dai, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215431/
https://www.ncbi.nlm.nih.gov/pubmed/30305304
http://dx.doi.org/10.1242/dmm.036632