Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders

The zebrafish (Danio rerio) has become a popular vertebrate model organism to study organ formation and function due to its optical clarity and rapid embryonic development. The use of genetically modified zebrafish has also allowed identification of new putative therapeutic drugs. So far, most studi...

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Detalles Bibliográficos
Autores principales: Tessadori, Federico, Roessler, Helen I., Savelberg, Sanne M. C., Chocron, Sonja, Kamel, Sarah M., Duran, Karen J., van Haelst, Mieke M., van Haaften, Gijs, Bakkers, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215435/
https://www.ncbi.nlm.nih.gov/pubmed/30355756
http://dx.doi.org/10.1242/dmm.035469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215435/
https://www.ncbi.nlm.nih.gov/pubmed/30355756
http://dx.doi.org/10.1242/dmm.035469

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