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Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders
The zebrafish (Danio rerio) has become a popular vertebrate model organism to study organ formation and function due to its optical clarity and rapid embryonic development. The use of genetically modified zebrafish has also allowed identification of new putative therapeutic drugs. So far, most studi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215435/ https://www.ncbi.nlm.nih.gov/pubmed/30355756 http://dx.doi.org/10.1242/dmm.035469 |