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FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium

Structural rearrangements of the genome can drive lung tumorigenesis through the generation of fusion genes with oncogenic properties. Advanced genomic approaches have identified the presence of a genetic fusion between fibroblast growth factor receptor 3 (FGFR3) and transforming acidic coiled-coil...

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Detalles Bibliográficos
Autores principales: Best, Sarah A., Harapas, Cassandra R., Kersbergen, Ariena, Rathi, Vivek, Asselin-Labat, Marie-Liesse, Sutherland, Kate D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215478/
https://www.ncbi.nlm.nih.gov/pubmed/29991799
http://dx.doi.org/10.1038/s41388-018-0399-5