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Mathematically universal and biologically consistent astrocytoma genotype encodes for transformation and predicts survival phenotype

DNA alterations have been observed in astrocytoma for decades. A copy-number genotype predictive of a survival phenotype was only discovered by using the generalized singular value decomposition (GSVD) formulated as a comparative spectral decomposition. Here, we use the GSVD to compare whole-genome...

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Detalles Bibliográficos
Autores principales: Aiello, Katherine A., Ponnapalli, Sri Priya, Alter, Orly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215493/
https://www.ncbi.nlm.nih.gov/pubmed/30397684
http://dx.doi.org/10.1063/1.5037882