Combination of Microwave-Assisted Girard Derivatization with Ionic Liquid Matrix for Sensitive MALDI-TOF MS Analysis of Human Serum N-Glycans

We developed a new method for MALDI-TOF MS detection of N-glycans derived from human serum. The synergistic combination of microwave-assisted Girard T derivatization, solid-phase extraction desalting, and an ionic liquid matrix (2, 5-dihydroxybenzoic acid/aniline) (GT-SPE-DHB/An) allowed of more sen...

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Detalles Bibliográficos
Autores principales: Le, Hoa Thi, Park, Kyu H., Jung, Woong, Park, Hyung Soon, Kim, Tae Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215560/
https://www.ncbi.nlm.nih.gov/pubmed/30420937
http://dx.doi.org/10.1155/2018/7832987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215560/
https://www.ncbi.nlm.nih.gov/pubmed/30420937
http://dx.doi.org/10.1155/2018/7832987

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