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βcatenin is a marker of poor clinical characteristics and suppressed immune infiltration in testicular germ cell tumors

BACKGROUND: WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. METHODS: Surgical specimens from 247 patients were analyzed. Βcatenin ex...

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Detalles Bibliográficos
Autores principales: Chovanec, Michal, Cierna, Zuzana, Miskovska, Viera, Machalekova, Katarina, Kalavska, Katarina, Rejlekova, Katarina, Svetlovska, Daniela, Macak, Dusan, Spanik, Stanislav, Kajo, Karol, Babal, Pavel, Mego, Michal, Mardiak, Jozef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215644/
https://www.ncbi.nlm.nih.gov/pubmed/30390643
http://dx.doi.org/10.1186/s12885-018-4929-x