Altered endotoxin responsiveness in healthy children with Down syndrome

BACKGROUND: Down syndrome (DS) is the most common syndromic immunodeficiency with an increased risk of infection, mortality from sepsis, and autoinflammation. Innate immune function is altered in DS and therefore we examined responses in CD11b and Toll like receptor 4 (TLR-4), which are important im...

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Detalles Bibliográficos
Autores principales: Huggard, Dean, McGrane, Fiona, Lagan, Niamh, Roche, Edna, Balfe, Joanne, Leahy, Timothy Ronan, Franklin, Orla, Moreno, Ana, Melo, Ashanty M., Doherty, Derek G., Molloy, Eleanor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215672/
https://www.ncbi.nlm.nih.gov/pubmed/30390640
http://dx.doi.org/10.1186/s12865-018-0270-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215672/
https://www.ncbi.nlm.nih.gov/pubmed/30390640
http://dx.doi.org/10.1186/s12865-018-0270-z

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